Guided Bone Regeneration:
The process of guided bone regeneration involves the use of bone fragments and a membrane, both biocompatible. The most important materials are:
Bone Grafts: These grafts are used to fill bone defects and expedite the bone regeneration process. There are four types of bone grafts:
- - Autogenous: These are bone fragments from the patient's own body.
- - Xenogeneic: These are bone fragments sourced from cattle.
- - Allogeneic: These are bone fragments from other human donors, typically obtained from bone banks.
- - Alloplastic: These are bone fragments from laboratories, synthetic grafts, and biocompatible materials.
Membranes: The purpose of membranes is to establish a physical-mechanical barrier between the gingival epithelium and the root surface. This is crucial because direct interaction between these structures can prevent periodontal ligament cells from returning to their proper location. Instead of bone regeneration, it can lead to continued gingival recession at the site, which is not the treatment goal. This approach is known as Guided Tissue Regeneration (GTR).
There are two types of membranes:
- - Non-absorbable: These membranes need to be removed after a period of 4 to 6 weeks.
- - Absorbable: There is no need to remove these membranes as they naturally dissolve.
It is important to note that both types of membranes must be completely covered by the gingiva along their entire length.
Additionally, chemical mediators are used to stimulate the differentiation of mesenchymal cells present in cementum, ligament, and bone. This promotes the transformation of mesenchymal cells into cementoblasts, fibroblasts, and osteoblasts, in that specific order, contributing to the tissue regeneration process.
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